Publications | Professional Publications
Click image to enlarge and view additional page images.	Alteration of Leukocyte Surface Potential in Response to Chemotactic Agents
	James Arthur Whitcomb
	PhD Dissertation. Indiana University School of Medicine, Indianapolis, IN
	1981. Pages: xii, 168. Hard Bound 8.5x11.
	Limited availability. Contact the author for more information.
Submitted to the faculty of the Graduate School in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Program of Medical Biophysics, Indiana University.
Polymorphonuclear leukocyte (PMN) stimulation by the chemotactic oligopeptide FMLP was shown to cause a significant surface potential change (p<0.001) of at least 14 mV at 10 minutes after stimulation by 0.1 uM FMLP. Morphometric analysis of transmission electron micrographs indicates a significant increase (p<0.001) in PMN surface area upon stimulation by FMLP. This increase results in an underestimate of the calculated surface potential change.
Adapted from the Abstract.
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